Thymineless recombination in Saccharomyces cerevisiae is independent of the ability to undergo meiosis |
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Authors: | Bernard A. Kunz J. Gerard Little Friederike Eckardt Robert H. Haynes |
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Affiliation: | (1) Biology Department, York University, M3J 1P3 Toronto, Ontario, Canada;(2) Gesellschaft für Strahlen- und Umweltforschung, D-8042 Neuherberg, Federal Republic of Germany;(3) Present address: Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, P.O. Box 12233, 27709 Research Triangle Park, NC, USA |
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Abstract: | Summary Thymine nucleotide starvation is recombinagenic in Saccharomyces cerevisiae and induces formation of the nuclear dense body, a structure characteristic of yeast cells in meiosis. Conceivably, thymineless recombination in yeast, presumed to be mitotic, might be meiotic in nature. We have tested this hypothesis and have found that thymineless recombination can be induced in strains incapable of meiotic exchange. |
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Keywords: | Thymineless recombination Meiosis |
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