| 2型糖尿病血栓前状态的检测及临床意义 |
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| 引用本文： | 周建耀,刘佳,朱晓燕. 2型糖尿病血栓前状态的检测及临床意义[J]. 中国误诊学杂志, 2003, 3(5): 651-652 |
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| 作者姓名： | 周建耀 刘佳 朱晓燕 |
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| 作者单位： | 福建省三明市第一医院血液科,365000 |
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| 摘 要： | 目的：探讨2型糖尿病患血栓前状态变化与血栓形成的关系及机理。方法：对96例2型糖尿病患测定6项能反映血栓前状态的分子标志物。结果：与正常对照组比较，各组糖尿病患血栓前状态指标均发生不同程度的变化。血浆vWF：Ag、血浆GMP—140、D—二聚体水平较正常明显升高，t—PA活性下降。结论：糖尿病患存在着血栓前状态及不同程度的血栓形成，血栓前状态指标的检测有助于判断糖尿病的病情及血管病变的程度。
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| 关 键 词： | 2型糖尿病 血栓前状态 检测 病理生理学 |
| 文章编号： | 1009-6647(2003)05-0651-02 |
| 修稿时间： | 2003-01-20 |
Clinical Significance of Measurement of Prethrombotic State in Patients with Type 2 Diabetes Mellitus |
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| ZHOU Jian yao,LIU Jia,ZHU Xiao yan. Clinical Significance of Measurement of Prethrombotic State in Patients with Type 2 Diabetes Mellitus[J]. Chinese Journal of Misdiagnostics, 2003, 3(5): 651-652 |
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| Authors: | ZHOU Jian yao LIU Jia ZHU Xiao yan |
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| Abstract: | Objective To explore the clinical significance of measurement of prethrombotic state in patients with type 2 diabetes mellitus. Methods Six parameters concerning endotheliocytes, platelets and fibrinolysis were measured in 96 cases of type 2 diabetes mellitus.Results As compared with normal controls, the levels of plasma vWF,GMP 140 and D Dimer were significantly higher, while the activity of t PA was significantly lower.Concluisons The measurement of prethrombotic state had very important clinical values in the early diagnosis and judgement of type 2 diabetes mellitus with microangiopathy. |
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| Keywords: | Diabetes mellitus non insulin dependent/physiopathology Diabetic angiopathies/diagnosis Thrombophilia/diagnosis |
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