In vitro velocity measurements down strem from the lonescu-Shiley aortic bioprosthesis in steady and pulsatile flow |
| |
Authors: | Hanle D. D. Harrison E. C. Yoganathan A. P. Corcoran W. H. |
| |
Affiliation: | (1) Chemical Engineering Laboratory, California Institute of Technology, CA Pasadena, 91125, USA;(2) Cardiology Section, Los Angeles County-University of Southern California Medical Center, 90033 Los Angeles, CA, USA;(3) BioFluid Dynamics Laboratory, School of Chemical Engineering, Georgia Institute of Technology, 30332 Atlanta, GA, USA;(4) Chemical Engineering Laboratory, California Institute of Technology, 91125 Pasadena, CA, USA;(5) Present address: Experimental Station, E.I. Du Pont de Nemours & Co. Inc., 19898 Wilmington, DE, USA |
| |
Abstract: | ![]() Velocity measurements were made in vitro using laser Doppler anemometry (LDA) downstream from an lonescu-Shiley (IS) bioprosthetic aortic heart valve. Velocity measurements were made in both steady and pulsatile flow. A systematic, flow mapping approach to the measurement methodology showed that the IS valve generated a large jetlike flow constriction. The acceleration ratio, defined as the maximum mean velocity for the IS valve divided by that for no valve obstructing the flow, was as high as 2·4 for steady flow and 2·6 for pulsatile flow. It was concluded that the IS valve generated a flow quite unlike that observed by other in vestigators for the natural human aortic valve, after which the leaflet design of the IS valve was modelled. In addition, a comparative analysis of steady and pulsatile results was undertaken. It was found that the pulsatile flow results for the systolic ejection interval could be divided into three phases, denoted early, mid, and late systole, as defined by the flow structure at the data plane location. Only during midsystole were the pulsatile flow results approximated by the steady flow results. Also, it was found that the magnitude of the flow disturbance measured in steady flow tended to be an upper bound on that measured for pulsatile flow. |
| |
Keywords: | Laser-Doppler anemometry Prosthetic heart valve Pulsatile flow Velocity measurements |
本文献已被 SpringerLink 等数据库收录! |
|