| 脐血铅与初乳铅含量与新生儿神经行为发育关系 |
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| 引用本文： | 刘康生,郝加虎,顾平清,孙慧谨,时娟,戴春芳,刘璇.脐血铅与初乳铅含量与新生儿神经行为发育关系[J].中国优生与遗传杂志,2012(2):25-28. |
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| 作者姓名： | 刘康生 郝加虎 顾平清 孙慧谨 时娟 戴春芳 刘璇 |
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| 作者单位： | 南京妇幼保健院检验科;安微医科大学公共卫生学院儿少妇幼系;南京妇幼保健院儿保科;南京妇幼保健院产科 |
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| 摘 要： | 目的 探讨在宫内低水平铅暴露状态下,新生儿脐血铅含量及初乳铅铅含量与神经行为发育的关系。方法 随机选取南京市妇幼保健院医院产科2010-01/04出生的足月新生儿170例。以脐血铅和初乳铅铅含量作为新生儿铅暴露的指标,新生儿神经行为（NBNA）发育评分作为效应指标,根据初乳铅中位数48.3μg/l,新生儿被分为高低铅两组。结果 高暴露组在新生儿主动肌张力、原始反射,和神经行为发育总评分上低于低暴露组,差异有统计学意义（P〈0.05）,在新生儿行为能力、被动肌张力、一般估价上差异无统计学意义。结论 初乳铅脐血铅水平和与婴儿的早期发育有关,铅可通过乳汁和脐血造成新生儿的铅接触,对新生儿婴儿早期神经行为发育产生不良影响。
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| 关 键 词： | 新生儿 脐血 初乳铅 血铅 神经行为 |
The effect of lead levels in the umbilical cord blood and foremilk on the neurobehavioral development of the neonates |
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| LIU Kang-sheng,HAO Jia-hu,GU Ping-qing,SUN Hui-jin,SHI Juan,DAI Chun-fang,LIU Xuan.The effect of lead levels in the umbilical cord blood and foremilk on the neurobehavioral development of the neonates[J].Chinese Journal of Birth Health & Heredity,2012(2):25-28. |
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| Authors: | LIU Kang-sheng HAO Jia-hu GU Ping-qing SUN Hui-jin SHI Juan DAI Chun-fang LIU Xuan |
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| Institution: | 1.Department of Clinical Laboratory of Nanjing Maternity and Child Health Care Hospital,210004,Nanjing,China;2.School of Public Health of Anhui Medical University,Department of Maternity and Child Health Care,230032,Hefei,China;3.Child Health Care Department of Nanjing Maternity and Child Health Care Hospital,210004,Nanjing,China;4.Obstetrical Department of Nanjing Maternity and Child Health Care Hospital,210004,Nanjing,China;5.Department of Clinical Laboratory,the Second Affiliated Hospital of Southeast University,Nanjing,210003,China) |
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| Abstract: | |
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| Keywords: | Foremilk Umbilical cord blood Lead Neurobehavioral development |
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