角膜移植术式的重大变化趋势

角膜移植手术是治疗多种角膜疾病的有效方法，有时是唯一方法。能否正确选择手术时机和手术方式，对于治疗效果至关重要。因手术技术的改进、对感染性角膜病较早采用板层角膜移植且疗效肯定、对穿透性角膜移植术后植片慢性失功等问题的发现、研究和认识，以及免疫排斥反应仍是角膜移植早期失败的主要原因，所以传统观念上穿透性角膜移植和板层角膜移植的适应证发生巨大变化，对传统的适应证提出了新的挑战。

Lamellar keratoplasty: problems and trend of corneal transplantation

Corneal transplantation has been an effective and sometimes the only one of effective method to treat some cornea diseases.It is crucial whether or not a doctor is able to choose the right timing and method of surgery.Because surgical techniques have been improved,the outcome of lamellar keratoplasty (LKP) for infective corneal diseases affirmed,chronic corneal allograft dysfunction after penetrating keratoplasty has been recognized and studied,and acute immunologic rejection is still regarded as the main reason for early graft failure,the conventional indications of penetrating keratoplasty (PKP) and LKP have been challenged and changed a lot.