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慢性乙型病毒性肝炎湿热中阻证血浆蛋白质组学分析
引用本文:魏嵋,王小栋,王磊琼,刘友平,李洪,郭芳宏. 慢性乙型病毒性肝炎湿热中阻证血浆蛋白质组学分析[J]. 中国中西医结合杂志, 2011, 31(10): 1341-1345
作者姓名:魏嵋  王小栋  王磊琼  刘友平  李洪  郭芳宏
作者单位:1. 泸州医学院中西医结合学院中医诊断学教研室(四川646000)
2. 泸州医学院生物化学教研室(四川646000)
3. 泸州医学院附属中医院肝胆内科(四川646000)
基金项目:四川省中医药管理局资助项目,四川省教育厅科技基金,四川省卫生厅科技基金
摘    要:目的 从蛋白质组学的角度探讨慢性乙型病毒性肝炎(chronic viral hepatitis B,CHB)湿热中阻证的本质内涵。

关 键 词:慢性乙型病毒性肝炎;湿热中阻证;血浆蛋白;蛋白质组学

Plasma Proteomic Analysis of Patients with Chronic Hepatitis B of Damp-heat Retention in the Middle-jiao Syndrome
WEI Mei,LIU You-ping and GUO Fang-hong. Plasma Proteomic Analysis of Patients with Chronic Hepatitis B of Damp-heat Retention in the Middle-jiao Syndrome[J]. Chinese journal of integrated traditional and Western medicine, 2011, 31(10): 1341-1345
Authors:WEI Mei  LIU You-ping  GUO Fang-hong
Affiliation:WEI Mei,LIU You-ping,GUO Fang-hong,et alDepartment of Chinese Medicine Diagnostics Research and Teaching,College of Integrative Medicine,Luzhou Medical College,Sichuan (646000)
Abstract:Objective To study the essence of chronic viral hepatitis B (CHB) of damp-heat retention in the middle-jiao syndrome (DRMS) from plasma proteomic angle. Methods Plasma proteomic analyses of plasmal whole protein of patients in the group with CHB of DRMS (20 cases) and subjects in the health control group (5 cases) were compared using two-dimensional gel electrophoresis (2-DE), mass spectrography, and other bioinformatics analyses methods. Results Eight protein dots with obvious regularity changes of differe...
Keywords:chronic viral hepatitis B  damp-heat retention in the middle-jiao syndrome  plasma protein  proteomic  
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