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北京268例疑似莱姆病患者抗伯氏疏螺旋体抗体检测结果分析
引用本文:张茂俊 万康林. 北京268例疑似莱姆病患者抗伯氏疏螺旋体抗体检测结果分析[J]. 疾病监测, 1998, 13(3): 85-90. DOI: 10.3784/j.issn.1003-9961.1998.3.85
作者姓名:张茂俊 万康林
作者单位:1.中国预防医学科学院流行病学微生物学研究所 102206
摘    要:
1995~1996年,应用IFA和ELISA两种试验方法对北京地区六大医院送检的268例临床疑似莱姆病患者血清进行了抗伯氏疏螺旋体IgM、IgG抗体检测,其中81例血清呈阳性反应,阳性率30.22%。神经系统病人150例,阳性59例,心血管系统病人25例,阳性6例,皮肤损伤病人34例,阳性7例,关节痛病人49例,阳性6例,头痛发热乏力病人7例,阳性2例,精神异常病人33例,阳性1例。81例抗体阳性病人应用抗生素治疗后,有效率达98%。

关 键 词:莱姆病   间接酶联免疫吸附试验   间接免疫荧光抗体试验
收稿时间:1997-10-14

Anti Borrelia Burgdorferi Antibody Response In 268 Patients With Suspected Lyme Disease In Beijing
Affiliation:1.Institute of Epidemidogy & Microbialogy;Beijing 102206
Abstract:
With an enzyme-linked immunosorbent assay (ELISA) and an indirect flouorescent antibody (IFA) test, an investigation on antibodies (IgG,IgM) of Borrdlia burgdorferi in sera of 268 suspected lyme disease patients was carried out from 1995 to 1996.Eighty one patients were positive (30.22%).The positive rate of the neurological disorders,circulatory system patients,skin disorders and arthritis patients was 39.33%(59/150),24.00%(6/25),20.59%(7/34) and 12.24%(6/49) respectively.Two specimens of the seven patients with headache,fatigue and fever were positive.Among the three psychiatric derangments,one specimen was positive.Ninety - eight percent of the total 81 positive patients had good curative effects after the treatment of antibiotic.
Keywords:Lyme Disease ELISA IFA  
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