南宁地区新生儿及婴幼儿TORCH检测结果分析

目的掌握本地区新生儿及婴幼儿TORCH感染情况及特点,为临床诊断及治疗提供依据。方法采用酶联免疫吸附试验检测患儿血清TORCH-IgM抗体,比较新生与婴幼儿抗体阳性率。结果 5920例患者中,TORCH-IgM阳性率为6.01%,新生儿和婴幼儿阳性率分别为3.40%和19.58%,以CMV阳性为主,且婴幼儿阳性率高于新生儿(P<0.01)。TORCH-IgM阳性患儿主要临床表现为肝炎综合征、病理性黄疸和肺炎。结论南宁地区新生儿及婴幼儿TORCH感染率较高,以CMV感染为主,且缺乏特异临床表现;加强高危人群TORCH筛查是降低出生缺陷发生率和减少患儿后遗症的有效措施,这对优生优育、提高人口素质具有重要意义。

Analysis on TORCH antibodies detected in neonates and infants

Objective: To investigate the prevalence and characteristic of the TORCH infection in Neonates and Infants,and provide basis for clinical diagnosis and treatment.Methods: TORCH-IgM antibody were detected by using enzyme linked immunosorbent assay method in the serum.Results: Among the 5920 cases,the overall infection rate of TORCH was 6.01%,and that were 3.40% and 19.58% in group of Neonates and Infants respectively.CMV was main pathogens,and the positive rate of TORCH-IgM in Neonates was higher than that in Infants.Hepatitis syndrome,pathological jaundice and pneumonia were the main clinical manifestations among the positive cases of TORCH-IgM.Conclusion: The positive rate of TORCH in Neonates and Infants was high in Nanning.the specific clinical manifestations of TORCH infection was lack.The surveillance of TORCH Infection should be performed among high-risk groups.