| 胰抗消胶囊干预2型糖尿病胰岛素抵抗的临床研究 |
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| 引用本文： | 陈娟,阎纳新,沈海平. 胰抗消胶囊干预2型糖尿病胰岛素抵抗的临床研究[J]. 河北中医, 2009, 31(11): 1611-1613 |
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| 作者姓名： | 陈娟 阎纳新 沈海平 |
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| 作者单位： | 河北省人民医院药学部,河北,石家庄,050051;河北省石家庄市第五医院药学部,河北,石家庄,050021;河北省人民医院中医科,河北,石家庄,050051 |
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| 基金项目： | 河北省科学技术研究与发展指导计划 |
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| 摘 要： | 目的观察胰抗消胶囊对2型糖尿病胰岛素抵抗的影响。方法将80例2型糖尿病患者随机分为治疗组46例和对照组34例,2组均予盐酸二甲双胍治疗口服,治疗组在此基础上予胰抗消胶囊口服。2组均8周为1个疗程。治疗前后分别测空腹血糖（FPC）、总胆固醇（TC）、甘油三酯（TG）、糖化血红蛋白（HbAlc）、空腹胰岛素（FINS）、胰岛素敏感性指数（ISI）。结果治疗组总有效率为93．48％,对照组总有效率为67．65％,2组比较差异有统计学意义（P〈0．05）,治疗组优于对照组;治疗组治疗后FPG、TC、TG、HbAlc、FINS、ISI水平与治疗前比较差异有统计学意义（P〈0．05）,对照组FPG、HbAlc、FINS、ISI水平与治疗前比较差异有统计学意义（P〈0．05）;治疗后2组间比较,治疗组TC、TG、FINS、ISI水平与对照组比较差异有统计学意义（P〈0．05）,治疗组优于对照组。结论胰抗消胶囊能明显改善2型糖尿病的胰岛素抵抗。
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| 关 键 词： | 糖尿病 2型 胰岛素抗药性 胶囊剂 中医药疗法 |
Clinical observation of Yikangxiao capsules on insulin resistance of type 2 diabetes |
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| CHEN Juan,YAN Naxin,SHEN Haiping. Clinical observation of Yikangxiao capsules on insulin resistance of type 2 diabetes[J]. Hebei Journal of Traditional Chinese Medicine, 2009, 31(11): 1611-1613 |
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| Authors: | CHEN Juan YAN Naxin SHEN Haiping |
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| Affiliation: | CHEN Juan,YAN Naxin,SHEN Haiping. Department of Pharmacy,Hebei Provincial People's Hospital,Hebei,Shijiazhuang 050051 |
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| Abstract: | Objective To observe the clinical efficacy of Yikangxiao capsules in improving type 2 diabetes insulin resistance. Methods 80 patients with type 2 diabetes were randomly divided into two groups:the control group (34 cases) was treated with Metformin,the treatment group (46 cases) was treated with combination of Yikangxiao capsules and Metformin. These two groups were all treated for 8 weeks. FPG,TC,TG,FINS,HbA1c and ISI were observed before and after treatment. Results The total effects in the treatment gro... |
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| Keywords: | Type 2 diabetes Insulin resistance Yikangxiao capsules |
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