| 临床分离金黄色葡萄球菌的耐药性分析 |
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| 引用本文： | 齐子芳,李恩杰,田立华. 临床分离金黄色葡萄球菌的耐药性分析[J]. 临床输血与检验, 2011, 13(1): 30-33. DOI: 10.3969/j.issn.1671-2587.2011.01.010 |
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| 作者姓名： | 齐子芳 李恩杰 田立华 |
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| 作者单位： | 山东省泰山医学院附属聊城市第二人民医院检验科,252600 |
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| 摘 要： | 目的分析金黄色葡萄球菌(SAU)临床分离株的耐药特性,为临床合理用药提供参考依据。方法细菌鉴定应用VITEK 32全自动细菌鉴定分析系统,采用K-B法对临床分离金黄色葡萄球菌菌株进行药物敏感性试验;头孢西丁和苯唑西林纸片扩散法检测MRSA;双纸片扩散法检测诱导型克林霉素耐药。结果 216株SAU中耐甲氧西林金黄色葡萄球菌(MRSA)130株,占60.2%;MRSA对青霉素G、氨苄西林100.0%耐药;对万古霉素、利奈唑烷100.0%敏感;对氯霉素耐药率为8.5%;对呋喃妥因耐药率为14.6%;对大环内酯类、喹诺酮类、氨基糖苷类抗菌药物耐药率均较高(61.5%～90.0%),且存在多药耐药;MRSA耐药率普遍高于MSSA。苯唑西林纸片扩散法较头孢西丁纸片扩散法判断MRSA的漏检率为4.6%;克林霉素诱导耐药检出率为56.3%。结论临床分离金黄色葡萄球菌耐药性已十分严重;头孢西丁纸片扩散法是检测MRSA简便、可靠的方法;临床微生物室应常规检测金黄色葡萄球菌红霉素对克林霉素的诱导耐药性,以指导临床正确使用抗菌药物。
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| 关 键 词： | 金黄色葡萄球菌 耐甲氧西林金黄色葡萄球菌 耐药性 诱导耐药 |
Drug Resistance of Staphylococcus Aureus Isolated from Clinic |
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| QI Zi-fang,LI En-jie,TIAN Li-Hua. Drug Resistance of Staphylococcus Aureus Isolated from Clinic[J]. Journal of Clinical Transfusion and Laboratory Medicine, 2011, 13(1): 30-33. DOI: 10.3969/j.issn.1671-2587.2011.01.010 |
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| Authors: | QI Zi-fang LI En-jie TIAN Li-Hua |
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| Affiliation: | QI Zi-fang,LI En-jie,TIAN Li-Hua.Depatrment of Microbiological Experiment,The Second People's Hospital of Liaocheng,Shandong,Liaocheng 252600 |
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| Abstract: | Objective To anlyse the antimicrobial agents resistance of Staphylococcus aureus isolated from clinic,so as to choose the effective antibiotics.Methods The pathogenic bacterias were evaluated by VITEK32,Drug susceptibility test was carried out by K-B way.MRSA was detected by cefoxitin disk and oxacillin disk.The inducible clindamycin resistance(D Test) was tested by double disk diffusion method.Results From 216 strains of staphylococcus aureus 130 strains of MRSA were detected,the rate was 60.2%.All MRSA st... |
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| Keywords: | Staphylococcus aureus MRSA Drug resistance Inducible resistance |
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