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血小板悬浮血浆ABO血型抗体效价与保存时间消长性研究
引用本文:忻玥,李志强. 血小板悬浮血浆ABO血型抗体效价与保存时间消长性研究[J]. 临床输血与检验, 2011, 13(1): 18-20. DOI: 10.3969/j.issn.1671-2587.2011.01.005
作者姓名:忻玥  李志强
作者单位:上海交通大学附属第六人民医院,200233
基金项目:上海市公共卫生重点学科建设项目(No.2007-2009)资助
摘    要:
目的研究单采血小板悬浮血浆中的抗-A和抗-B效价及其与保存时间的相关性。方法应用盐水凝集法检测血浆IgM抗-A、抗-B效价;应用2-巯基乙醇(2-Me)破坏IgM抗体后,抗人球蛋白法检测血浆IgG抗-A、抗-B效价。结果在保存期内A、B、O型单采血小板悬浮血浆中抗-A(IgM或/和IgG)或/和抗-B(IgM或/和IgG)效价间相互比较差异无统计学意义(P>0.05),其效价不随保存时间延长而降低(P>0.05);10%O型单采血小板悬浮血浆中抗-A和抗-B效价均较高。结论单采血小板输注时可不进行血液交叉配合试验,但须同型输注;尤其是O型悬浮血浆含较高的抗-A或/和抗-B(IgM或/和IgG)效价时,不能输注给其他血型患者。

关 键 词:血小板  血浆  抗体  效价  

Study on the Relationship between ABO Blood Antibody Titer and Save Time in Platelet Suspended Plasma
XING Yue,LI Zhi-qiang. Study on the Relationship between ABO Blood Antibody Titer and Save Time in Platelet Suspended Plasma[J]. Journal of Clinical Transfusion and Laboratory Medicine, 2011, 13(1): 18-20. DOI: 10.3969/j.issn.1671-2587.2011.01.005
Authors:XING Yue  LI Zhi-qiang
Affiliation:.(Sixth People′s Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200233 )
Abstract:
Objective To study the relationship between anti-A /anti-B antibody titer and save time in platelet suspended plasma.Methods IgM anti-A /anti-B antibody titers in plasma were tested using saline agglutination method.IgG anti-A /anti-B antibody titers were detected by anti-human globulin method after the destruction of IgM antibody using 2-mercaptoethanol(2-Me).Results There were no significant differences(P>0.05) between anti-A(IgM or IgG) and anti-B(IgM or IgG) antibody titers in the platelet suspended pla...
Keywords:Platelet Plasma Antibody Titer  
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