星状神经节阻滞在防治乳腺癌术后皮下积液中的应用

目的: 评价星状神经节阻滞(SGB)对乳腺癌改良根治术后常见并发症皮下积液的防治效果。 方法: 215例乳腺癌改良根治术患者按照随机临床试验设计分为2组,对照组108例给予临床常规局部加压包扎法进行治疗,干预组107例在上述传统治疗措施基础上合并实施星状神经节阻滞(SGB);治疗效果的评价指标主要包括:置引流管时间、平均日引流量、皮下积液率、皮瓣坏死率、切口I期愈合率。 结果 :对照组和干预组平均置引流管时间分别为9.8和7.3d,平均日引流量分别为170ml和144ml,皮下积液的发生率分别为31%和13%,皮瓣坏死率分别为12%和4%,切口I期愈合率分别为67%和82%,经统计学检验,以上差别均具有显著性意义(P<0.05)。 结论: 对于本次乳腺癌改良根治术后皮下积液的干预研究发现,较临床上传统的单纯局部加压包扎法这种治疗手段相比,星状神经节阻滞联合疗法在防治皮下积液及皮瓣坏死方面表现出更佳的效果,能够促进乳腺癌改良根治术后患者皮下积液尽早得以治愈。

The Application of Stellate Ganglion Block in Prevention of Seroma after Modified Radical Mastectomy of Breast Cancer

Objective: To evaluate the effects of stellate ganglion block (SGB) on preventing seroma after modifiedradical mastectomy of breast cancer. Methods: A total of 215 patients were collected and randomly divided into twogroups. Patients in the control group were treated with traditional local compressed binding, and those in the interventiongroup were treated with SGB besides the upper traditional measure. The evaluating indices included the duration of pa-tients' bearing drainage tube, the average daily amount of drainage, the incidence rate of seroma and skin flap necrosisand the first phase concrescence rate of incision. Results: The duration of patients bearing drainage tube in the controland intervention group was 9.8 days and 7.3 days respectively; the average daily amount of drainage was 170ml and144ml respectively; the incidence rate of seroma was 31% and 13% respectively; the incidence rate of skin flap necrosiswas 12% and 4% respectively; and the first phase concrescence rate of incision was 67% and 82% respectively. Signifi-cant differences were found in all these indicators between the two groups(P<0.05). Conclusion: Compared with traditionallocal compressed binding, SGB combined with local compressed binding can prevent seroma after modified radical mas-tectomy of breast cancer.