Morphological and molecular basis of ovarian serous carcinoma |
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| Authors: | Daniel G Rosen a Zhihong Zhang a b Weiwei Shan a Jinsong Liu a a |
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| Affiliation: | Daniel G Rosen a,Zhihong Zhang a,b,Weiwei Shan a,Jinsong Liu a a Department of Pathology,the University of Texas M.D.Anderson Cancer Center,Houston,TX 77030,USA b Department of Pathology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu Province,China |
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| Abstract: | ![]()
Serous carcinoma is the most common type of epithelial ovarian cancer.In this review,we provide a comprehensive picture of ovarian serous cancers from multiple aspects:the first part of this review summarizes the morphological,histological,and immunological signatures of ovarian serous carcinoma;subsequently,we review the history of the evolvement of different grading systems used in ovarian serous cancer;in the end,we focus on characterizing the genetics that underlie the 2-tiered pathways through which ov... |
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| Keywords: | ovarian carcinoma grading morphology molecular genetics tumorigenesis |
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