| 芪丹通脉片对健康犬冠状动脉血流量及阻力影响 |
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| 引用本文： | 马静,王宗仁,马世平,行利,龙铟.芪丹通脉片对健康犬冠状动脉血流量及阻力影响[J].安徽中医学院学报,2001,20(3):45-47. |
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| 作者姓名： | 马静 王宗仁 马世平 行利 龙铟 |
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| 作者单位： | 中国人民解放军第四军医大学西京医院中医科, |
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| 基金项目： | 陕西省科技攻关项目;97K12-G5; |
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| 摘 要： | 目的：观察复方中药制剂芪丹通脉片对健康犬心脏冠状动脉血流量及阻力的影响，方法：分离犬的冠状动物左旋支及主动脉根部，放置电磁流量计探头，测定不同药物在给药前后不同时刻碱诉冠状动脉血流量，计算冠状动脉阻力。结果：芪丹通脉片高剂量（生药2g/kg)能明显增加冠状动脉血流量，减少冠状动脉阻力，结论：芪丹通脉片能够增加冠状动脉血流量，调整和改善心肌供血，为缺血性心脏病的治疗提供了实验论据。
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| 关 键 词： | 缺血性心脏病 冠状动脉血流量 冠状动脉阻力 芪丹通脉片 实验研究 |
| 文章编号： | 1000-2219(2001)03-0045-02 |
| 修稿时间： | 2001年2月7日 |
EFFECT OF QIDAN TONGMAI TABLET ON HEALTHFUL CANINE CORONARY BLOOD FLOW AND CORONARY RESISTANCE |
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| MA Jing,WANG Zong-ren,HANG Li,MA Shi-ping,LONG Yin.EFFECT OF QIDAN TONGMAI TABLET ON HEALTHFUL CANINE CORONARY BLOOD FLOW AND CORONARY RESISTANCE[J].Journal of Anhui Traditional Chinese Medical College,2001,20(3):45-47. |
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| Authors: | MA Jing WANG Zong-ren HANG Li MA Shi-ping LONG Yin |
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| Abstract: | Objective:To observe the effects of Qidan Tongmai tablet(QDTMT) on coronary blood flow and coronary resistance in healthful canine.Method:The canine circumflex branch of left coronary artery to root of aorta were separated.A probe of electromagnetic flow-meter was set in them.Coronary blood flow was measured before adminstration,and also detected at different time points after adminstration.Coronary resistance was calculated.Result:High dosage QDTMT significantly increased canine coronary blood flow(P<0.05),markedly reduced coronary resistance(P<0.05).Conclusion:QDTMT can improve coronary artery blood flow,adjust blood supply of cardiac muscle,and can be used in the prevention and treatment of ischemic cardiac disease. |
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| Keywords: | Ischemic cardiac disease Coronary bood flow Coronary resistance Qidan Tongmai tablet |
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