超声引导下射频消融治疗子宫肌瘤的研究进展

子宫肌瘤又称平滑肌瘤或肌瘤，是女性生殖器官最常见的良性肿瘤，由平滑肌和结缔组织组成，常见于30～50岁妇女，发病率约20%。子宫肌瘤的治疗包括保守治疗及手术治疗，其中射频消融（RFA）是一种微创治疗手段，目前已应用于多种疾病，在治疗妇科良性疾病方面的价值也得到了充分的认可。理想的RFA是运用热能以微创的方式、不损伤邻近正常组织的前提下，使靶组织遭受到彻底的破坏。现从作用机制、超声造影技术的临床应用、疗效评价、对生育功能的影响、安全性和有效性、影响因素等方面对RFA治疗子宫肌瘤进行简要概述。

Progress of Ultrasound-guided Radiofrequency Ablation for Uterine Fibroids

Uterine fibroids (UFs), also known as leiomyomas or myomas commonly seen at women of age of 30-50 years old, are the most prevalent benign tumors in female reproductive organs. UFs are composed of smooth muscle and connective tissue, reportedly occurring in 20% of this population. The treatment of UFs include conservative treatment and surgical treatment, of which radiofrequency ablation (RFA) is a minimally invasive treatment for the latter, and has been applied to a variety of diseases. Its value in the treatment of benign gynecological diseases has also been fully recognized. The ideal RFA is to use heat energy in a minimally invasive manner without damaging the adjacent normal tissue and to destroy the target tissue completely. This article shows a brief overview of RFA for uterine fibroids in the mechanisms, clinical application of ultrasonography, the evaluation of the curative effects, influence on fertility function, safety and effectiveness and the influencing factors of RFA of uterine fibroids.