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Therapeutic efficacy of clindamycin in combination with quinine for treating uncomplicated malaria in a village dispensary in Gabon
Authors:Michel Vaillant  Pascal Millet  Adrian Luty  Paul Tshopamba  Faustin Lekoulou  Justice Mayombo  Alain J. Georges  Philippe Deloron
Affiliation:Centre International de Recherches Médicales de Franceville, Franceville, Gabon
Abstract:
The efficacy of a 3-day clindamycin-quinine regimen to treat clinical malaria attacks was investigated in 256 children from western Gabon. Treatment was well tolerated by all of the children and its efficacy was higher than 97% by day 20. Thus this 3-day clindamycin-quinine regimen might constitute a potential alternative to chloroquine for treating clinical malarial attacks in children from Gabon.
Keywords:Malaria    Plasmodium falciparum    quinine    clindamycin    Gabon
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