糖尿病对倍频视野计检查结果的影响

目的 为了了解糖尿病是否导致青光眼倍频视野计(FDT)视野筛查中假阳性的因素;探讨随着糖尿病性视网膜病变的加重,FDT的变化情况.方法 对20名正常人和68例糖尿病患者(27例无明显视网膜病变、13例轻度非增生性糖尿病性视网膜病变NPDR、21例中度NPDR、7例重度NPDR)进行FDT(C-20-5)检查,并进行对比,FDT计分方法采用4个象限计分.结果 糖尿病但眼底镜下无明显视网膜病变患者的FDT视野异常例数为5例(18.52%),正常人为3名(15.00%)(P＜0.001);FDT计分与糖尿病患者视网膜病变程度呈正相关(p＜0.001).结论 糖尿病无明显视网膜病变患者的FDT视野缺损,发生率高于正常人;随着糖尿病视网膜病变的加重,FDT视野缺损也逐渐加重.糖尿病可能是导致青光眼FDT视野筛查中假阳性的因素.

Impact of diabetes mellitus on the results of frequency-doubling perimetry

Objective To investigate whether diabetes is a potential source of abnormal test results in glaucoma screening by use of frequency-doubling perimetry.To observe the change of FDT with the develop ment of clinical diabetic refinopathy disease severity scales.Methods 20 normal controls and 68 patients with diabetes were performed with the C-20-5 screening mode of the FDT device.The diabetic retinopathy disease severity levels consist of no apparent retinopathy.mild nonproliferative diabetic retinopathy(NPDR).moderate NPDR.severe NPDR.FDT score was by quadrant.Results The number of FDT visual field loss in no apparent retinopathy is 5,and normal subjects are 3(P＜0.001)；There was positive correlation between FDT scores and the diabetic retinopathy disease severity levels(P0.001).Conclusions FDT scores were higher in patients with no apparent retinopathy than in normal contrals.FDT scores increased with the diabetic retinopathy disease severity levels.Diabetes may be a source of false-positive test results when this technology is used for glaucoma screening.