Cocaine decreases self-control in rats: a preliminary report |
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| Authors: | A. W. Logue Henry Tobin John J. Chelonis Rex Y. Wang Nori Geary Stanley Schachter |
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| Affiliation: | (1) Department of Psychology, State University of New York at Stony Brook, 11794 Stony Brook, NY, USA;(2) Department of Psychiatry, State University of New York at Stony Brook, 11794 Stony Brook, NY, USA;(3) Bourne Laboratory, New York Hospital-Cornell University Medical Center, 21 Bloomingdale Road, 10605 White Plains, NY, USA;(4) Department of Psychology, Columbia University, 10027 New York, NY, USA |
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| Abstract: | Cocaine abuse is often associated with behavior that takes into account short-term, but not long-term consequences. However, there has been no empirical research concerning the effects of cocaine on self-control (choice of a larger, more delayed reinforcer over a smaller, less delayed reinforcer). In the present research, when food-deprived rats repeatedly chose between a larger, more delayed food reinforcer and a smaller, less delayed food reinforcer, chronic intraperitoneal injections of 15 mg/kg cocaine (but not 10 mg/kg fluoxetine) decreased the rats' choices of the larger, more delayed reinforcer. Cocaine can decrease rats' self-control. |
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| Keywords: | Cocaine Fluoxetine Self-control Choice Amount of reinforcement Delay of reinforcement Rats |
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