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Evaluation of the curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain on the patients with post stroke depression associated with anxiety
Authors:Yanjun WANG  Yixu HAN  Yutong HU  Lihua ZHANG
Affiliation:1. Department of Acupuncture–Moxibustion, Hebei Province Traditional Chinese Medicine Hospital, Shijiazhuang 050011, Hebei Province, China (河北省中医院针灸科, 石家庄 050011, 中国);2. Hospital of Traditional Chinese Medicine of Zhongshan, Zhongshan 528400, Guangdong Province, China (广东省中山市中医院,中山 528400, 中国);3. Rehabilitation Department, Cangzhou Hospital of Integrated TCM-WM, Cangzhou 061000, Hebei Province, China (河北省沧州中西医结合医院康复科, 沧州 061000, 中国)
Abstract:

Objective

To observe the comprehensive curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain for post stroke depression associated with anxiety.

Methods

Sixty-four patients with post stroke depression associated with anxiety were randomly divided into 2 groups according to the random numbers generated by spss16.0 software, the group of acupuncture manipulation of regulating governor vessel and unblocking brain (group A) and medication group (group B), with 32 patients in each group. Acupuncture manipulation of regulating governor vessel and unblocking brain was performed in group A, B?ihuì (百会GV 20), Shéntíng (神庭GV 24), Y?mén (哑门GV 15) and Dànzhōng (膻中CV 17), Gānshū (肝俞BL 18), Xīnshū (心俞BL 15), Shènshū (肾俞BL 23), Tàichōng (太冲LR 3), Tàixī (太溪KI 3), Shénmén (神门HT 7) and Nèiguān (内关PC 6) were selected. The treatment was conducted for once a day, and 5 times a week. Escitalopram oxalate tablets were given orally to the patients in group B for once a day. The treatment was conducted for 8 consecutive weeks in each group. The scores of Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA), Barthel index (BI) and Fugl–Meyer assessment (FMA) in the two groups before and after treatment were compared.

Results

Comparison with the same group before treatment, HAMD score and HAMA sore in the two groups after treatment for 4 weeks and 8 weeks were all obviously lower than that in the same group before treatment (all P?P?P?P?P?>?0.05); after treatment for 8 weeks, FMA score in group A was obviously higher than that in group B (P?P?>?0.05).

Conclusion

The curative effect of acupuncture manipulation of regulating governor vessel and unblocking brain on the anxiety state and motor function of the patients with post stroke depression is superior to that of escitalopram. With regard to the improvement of depression, this acupuncture manipulation was provided with the characteristic of rapid onset, and its long-term efficacy is equivalent to that of escitalopram. In terms of the improvement of activities of daily living, the curative effect of the two methods is equally well.
Keywords:Regulate the governor vessel  Acupuncture  Post stroke depression  Anxiety  Escitalopram oxalate
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