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正交实验法优选芙蓉膏提取工艺
引用本文:邾枝花,夏伦祝. 正交实验法优选芙蓉膏提取工艺[J]. 安徽医药, 2005, 9(4): 252-253
作者姓名:邾枝花  夏伦祝
作者单位:安徽中医学院,安徽,合肥,230038;安徽中医学院第一附属医院药剂科,安徽,合肥,230038
摘    要:
目的用正交实验法优选芙蓉膏提取工艺.方法以槲皮素含量、新藤黄酸含量及浸膏得率为评价指标,选择乙醇浓度(%)、加醇量(倍)、提取时间(h)和提取次数为考察因素,选用L9(34)正交试验确定芙蓉膏的提取工艺.结果以A3B1C3D2即6倍量80%乙醇提取3 h,共提2次为最佳工艺条件.结论该法提取效率高,稳定性好.

关 键 词:芙蓉膏  正交实验  槲皮素  新藤黄酸
收稿时间:2005-01-11
修稿时间:2005-01-11

Optimization of furong ointment's extraction technics by orthogonal design
ZHU Zhi-hua,XIA Lun-zhu. Optimization of furong ointment's extraction technics by orthogonal design[J]. Anhui Medical and Pharmaceutical Journal, 2005, 9(4): 252-253
Authors:ZHU Zhi-hua  XIA Lun-zhu
Abstract:
Aim To optimize extraction technics of furong ointment. Methods Assessment indexes are quercetin,neogambogic acid and extraction rate of extractum. We choose orthogonal design to optimize the extraction technics.Results The optimum extraction technics conditions are as follows: adding 6 folds of 80% ethanol, extracting twice times and 3 hours every time. Conclusion The method has high rate of extraction and good stability.
Keywords:furong ointment    orthogonal design    quercetin    neogambogic acid
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