帕瑞昔布钠在腹腔镜手术后镇痛的应用进展

腹腔镜手术比开腹手术有创伤小、术后恢复快等优势,但腹腔镜手术后仍有轻度到中度疼痛。一般临床术后镇痛常用阿片类药物,效果确切。但阿片类药物的不良反应也比较多,患者难以耐受。帕瑞昔布钠是即可静脉注射又可肌肉注射使用的特异性环氧化酶-2抑制剂,具有较好的抗炎镇痛效果。本文就帕瑞昔布钠在腹腔镜术后镇痛中的应用作一综述。

Progress on Analgesia Application of Parecoxib Sodium in Laparoscopic Surgery

Laparoscopic surgery has more advantages such as less trauma,quick recovery after operation than the open operation,but there is pain from mild to moderate after laparoscopic surgery.Clinically,the opioids are commonly used for postoperative analgesia,and it is effective well.But there are many adverse effects about the opioids,and patients cann’t tolerate them.Parecoxib,which can be both intravenous and intramuscular injection,is a specific cyclooxygenase-2 inhibitor.It is good to anti-inflammatory and analgesia.This article is a review on analgesia application of parecoxib sodium in laparoscopic surgery.