我国居民吸烟与脑卒中关系的Meta-analysis

应用随机效应模型 (法 )对国内 16篇吸烟与脑卒中关系的流行病学研究文献进行综合定量分析 ,结果表明吸烟与脑卒中有关 ,总合并 OR(95 % CI)为 1.5 4(1.2 6～ 1.88)。按脑卒中类型分层合并分析 ,结果吸烟与缺血型脑卒中、出血型脑卒中和脑卒中 (未分型 )联系的 OR分别为 1.70 (1.19～ 2 .43)、1.34 (0 .91～ 1.78)和 1.75 (1.32～2 .33)。并且还表明吸烟与脑卒中之间存在剂量效应关系。研究认为吸烟是我国居民脑卒中及其亚型的危险因素 ,控制吸烟是脑卒中病因预防的一项重要措施。

Meta-analysis of Smoking and Risk of Stroke in China

In the paper,a meta analysis was used to analyze the relations among 16 epidemological studies.The results showed that statistically significant correlation existed between smoking and risk of stroke.The total pooling OR (95%) was 1 54(1 26~1 88) for all studies.The pooling OR values (95%CI) of smoking with ischemic stroke,hemorrhagic stroke and stroke were 1 70(1 19~2 43),1 34(0 91~1 78) and 1 75(1 32~2 33) respectively.There was a strong dose response relation between the amount of smoking and stroke.This Meta analysis suggested that smoking be an important risk factor for stroke in China.;