Performance of ELF Serum Markers in Predicting Fibrosis Stage in Pediatric Non-Alcoholic Fatty Liver Disease |
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| Authors: | Nobili Valerio Parkes Julie Bottazzo Gianfranco Marcellini Matilde Cross Richard Newman Daniel Vizzutti Francesco Pinzani Massimo Rosenberg William M |
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| Affiliation: | Liver Unit, Bambino Gesù Children's Hospital and Research Institute, Rome, Italy. nobili66@yahoo.it |
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| Abstract: | ![]()
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| Keywords: | ALP, alkaline-phosphate ALT, alanine aminotransferase AST, aspartate aminotransferase AUROC, area under ROC BMI, body mass index CI, confidence interval CLD, chronic liver disease ELF, enhanced liver fibrosis HA, hyaluronic acid HABP, hyaluronic acid binding protein HOMA, homeostatic model assessment INR, international normalized ratio ISI, insulin sensitivity index IQR, interquartile range γ-GT, gamma glutamil-transpeptidase +LR, positive likelihood ratio &minus LR, negative likelihood ratio MAbs, monoclonal antibodies OC, receiver operating characteristic OGTT, oral glucose tolerance test NAFLD, nonalcoholic fatty liver disease NAS, NAFLD Activity Score NASH, nonalcoholic steatohepatitis PIIINP, amino-terminal propeptide of type III collagen PPV, positive predictive value S, sensitivity SD, standard deviation Sp, specificity NPV, negative predictive value TIMP-1, tissue inhibitor of metalloproteinase 1 |
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