| 差示分光光度法同时测定抑痤凝胶剂中2种成分的含量 |
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| 引用本文： | 夏曙辉,张月娟,单夕凤,张燕.差示分光光度法同时测定抑痤凝胶剂中2种成分的含量[J].中国药业,2006,15(2):36-37. |
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| 作者姓名： | 夏曙辉 张月娟 单夕凤 张燕 |
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| 作者单位： | 1. 中国人民解放军南京军区南京总医院,江苏,南京,210002
2. 江苏省盐城卫校,江苏,盐城,224231 |
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| 摘 要： | 目的：建立抑痤凝胶刺中甲硝唑和氯霉素的含量测定方法。方法：采用差示分光光度法，分别以0．1mol／L的盐酸和水为溶荆，278nm和320nm为测定波长，不经分离直接测定两组分含量。结果：被测组分的浓度与吸收度之间有良好的线性关系，r=0．9995。甲硝唑和氯霉素的平均回收率分别为99．46％和98．79％，RSD分别为0．93％和0、94％。结论：该法简便、快速、重现性好，消除了两组分之间的相互干扰．结果满意。
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| 关 键 词： | 甲硝唑 氯霉素 差示分光光度法 |
| 文章编号： | 1006-4931(2006)02-0036-02 |
| 收稿时间： | 03 9 2005 12:00AM |
| 修稿时间： | 05 8 2005 12:00AM |
Determination of 2 Components in Yizuo Mucilages by Differential Spectrophotometry |
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| Xia Shuhui,Zhang Yuejuan,San Xifeng,Zhang Yan.Determination of 2 Components in Yizuo Mucilages by Differential Spectrophotometry[J].China Pharmaceuticals,2006,15(2):36-37. |
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| Authors: | Xia Shuhui Zhang Yuejuan San Xifeng Zhang Yan |
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| Institution: | 1. Nanjing General Hospital of Nanjing Military Area, Nanjing, Jiangsu, China 210002; 2. Grade 99, Hygiene School of Yancheng, Yaneheng, Jiaagsu, China 224231 |
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| Abstract: | Objective: To establish a method to determine two components metronidazole and chloramphenicol in Yizuo mucilages. Methods: The two components were determined directly by differential spectrophotometry. The solvents were 0. 1 mol/L hydrochloric acid and water. The detecting wavelengths were at 278 nm and 320 nm, respectively. Results: The result showed a good linear relationship between the concentration and the absorbance of the two components. The respective correlation coefficients were 0. 999 5. The average recovery of metronidazole and chloramphenicol were 99. 46% ( RSD = 0. 93% ) and 98. 79% ( RSD = 0. 94% ), respectively. Conclusion: The method was simple, rapid and repeatable. The interference between two components each other can be eliminated and the result is reliable. |
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| Keywords: | metronidazole chloramphenicol differential speetrophotometry |
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