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肠易激综合征血浆及乙状结肠粘膜中生长抑素的变化
引用本文:杨云生 张万岱. 肠易激综合征血浆及乙状结肠粘膜中生长抑素的变化[J]. 临床消化病杂志, 1996, 8(4): 159-161
作者姓名:杨云生 张万岱
作者单位:[1]第四军医大学西京医院全军消化病研究所 [2]第一军医大学南方医院
摘    要:
应用放射免疫分析法检测正常组24例及肠易激综合征组26例受检者血浆及乙状结肠粘膜中生长抑素的含量,旨在探讨IBS患者历浆及乙状结肠粘膜中SS的含量有无变化,以及它在IBS疾病过程中的可能作用和临床意义。结果;IBS组血浆中SS的浓度明显高于正常组;乙状结肠粘膜中的SS的含量痛秘型IBS显著高于痛泻型,痛泻型IBS显著高于正常组。

关 键 词:肠易激综合征 生长抑素 乙状结肠 结肠粘膜

Somatostatin in Plasma and Sigmoid Mucosa in Irritable Bowel Syndrome
Yang Yun-sheng,Zhang Wan-dai,Zhou Dian-yuan,et alInstitute of Digestive Diseases,Xijing Hospital,Fourth Medical University of PLA,Xi''''an. Somatostatin in Plasma and Sigmoid Mucosa in Irritable Bowel Syndrome[J]. Chinese Journal of Clinical Gastroenterology, 1996, 8(4): 159-161
Authors:Yang Yun-sheng  Zhang Wan-dai  Zhou Dian-yuan  et alInstitute of Digestive Diseases  Xijing Hospital  Fourth Medical University of PLA  Xi''''an
Abstract:
The aim of this paper is to investigate the possible role and clinical significance of somatostatin(ss)in the irritable bowel syndrome(IBS). The somatostatin in plasma and sigmoid mucosa was measured by the radioimmunoassay in normal group(n = 24) and the IBS' group(n =26). Results: the plasma SS in the IBS' group was significantly higher than that in normal group(P<0. 05), the SS of the sigmoid mucosa in the IBS with predominant constipation was significantly more elevated than that in the IBS with predominant diarrhea (P<0.05) and the SS of the sigmoid mucosa in the IBS with predominant diarrhea was significantly higher than that in the normal group ( P < 0. 05). Conclusion: SS may play some role in the IBS' process and may have potential diagnostic value for the IBS in clinical experiment.
Keywords:Irritable bowel syndrome Somatostatin
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