胃食管反流病的研究进展

胃食管反流病在国内十分常见,发病率也逐年升高,患者的临床表现复杂多样,大部分表现为典型的胃烧灼感及反流症状,少部分患者表现为咽喉或呼吸系统等食管外症候,极少部分并发Barrett食管及食管腺癌。该病发病机制复杂,危险因素众多,严重影响人们的生活质量,且目前对该病的诊断标准尚未达成统一意见。国内外关于本病的发病机制及危险因素的研究较多,这些深入研究也促进了胃食管反流病诊断技术的不断发展。

Research Progress of Gastroesophageal Reflux Disease

Gastroesophageal reflux disease is very common in China, and its incidence has been increasing annually. The clinical manifestations are complex and diverse, mostly stomach burning and reflux, and a small number of extraesophageal symptoms like throat or respiratory discomfort, few with Barrett＇s esophagus and esophageal adenocarcinoma. The disease is seriously affecting people＇s quality of life, and its pathogenesis is complex,risk factors are wide-ranging. So far the diagnostic criteria has not yet reached a unified opinion. There are plenty of studies exploring the pathogeuesis and the risks ,which have promoted the development of new diagnostic technique for gastroesophageal reflux disease.