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| 毛细管电泳手性拆分方法的研发策略 | |
| 引用本文： | 陈伟成,刘长海,张海,朱臻宇,赵亮,张国庆,柴逸峰. 毛细管电泳手性拆分方法的研发策略[J]. 药学实践杂志, 2010, 28(2): 130-133 |
| 作者姓名： | 陈伟成 刘长海 张海 朱臻宇 赵亮 张国庆 柴逸峰 |
| 作者单位： | 1. 上海市南汇区中心医院药剂科,上海,201300 2. 第二军医大学,药学院药物分析教研室,上海,200433 3. 第二军医大学,东方肝胆外科医院药材科,上海,200438 |
| 摘 要： | 本文总结了毛细管电泳手性拆分的基本策略、分离条件选择策略、环糊精体系的选择,并提出毛细管电泳手性拆分方法的一般研究与开发策略,可为以后的毛细管电泳手性分离分析提供借鉴与思路。 |
| 关 键 词： | 毛细管电泳 手性拆分 研发策略 |
| 收稿时间： | 2009-10-21 |
| 修稿时间： | 2009-12-03 |
Research strategy of chiral separation by capillary electrophoresis |
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| CHEN Wei-cheng,LIU Chang-hai,ZHANG Hai,ZHU Zhen-yu,ZHAO Liang,ZHANG Guo-qing and CHAI Yi-feng. Research strategy of chiral separation by capillary electrophoresis[J]. The Journal of Pharmaceutical Practice, 2010, 28(2): 130-133 | |
| Authors: | CHEN Wei-cheng LIU Chang-hai ZHANG Hai ZHU Zhen-yu ZHAO Liang ZHANG Guo-qing CHAI Yi-feng |
| Affiliation: | Department of Pharmacy,Shanghai Nanhui Central Hospital,Shanghai 201300,China;Second Military Medical University,Department of Pharmaceutical Analysis,School of Pharmacy,Shanghai 200433;Second Military Medical University,Department of Pharmacy,Eastern Hepatobiliary Surgery Hospital,Shanghai 200438,China;Second Military Medical University,Department of Pharmaceutical Analysis,School of Pharmacy,Shanghai 200433;Second Military Medical University,Department of Pharmacy,Eastern Hepatobiliary Surgery Hospital,Shanghai 200438,China;Second Military Medical University,Department of Pharmacy,Eastern Hepatobiliary Surgery Hospital,Shanghai 200438,China;Second Military Medical University,Department of Pharmaceutical Analysis,School of Pharmacy,Shanghai 200433 |
| Abstract: | The selection method of separation condition and cyclodextrin and strategy of chiral separation by capillary electrophoresis were summarized,and a general research and development strategy was proposed,which can provide basis for chiral separation by capillary electrophoresis. |
| Keywords: | capillary electrophoresis chiral separation research strategy |
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