| 牛黄解毒片致患儿过敏性休克死亡1例 |
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| 引用本文： | 杨义,孙淑波,雷力力,聂磊.牛黄解毒片致患儿过敏性休克死亡1例[J].药物不良反应杂志,2010,12(2):147-147. |
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| 作者姓名： | 杨义 孙淑波 雷力力 聂磊 |
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| 作者单位： | 1. 佳木斯大学附属第一医院药剂科,黑龙江,佳木斯,154003
2. 佳木斯大学附属第一医院儿二科,黑龙江,佳木斯,154003 |
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| 摘 要： | 1例1岁半男性患儿,因大便干燥家长自行给予牛黄解毒片1片。1h后患儿出现颜面水肿,随后抽搐,颜面及四肢末梢发绀,呼吸心跳停止,遂入院。查体：昏迷状态,对光反射迟钝,R60～80次/min,BP35/0mmHg。实验室检查：ALT368.00U/L,AST2000.00U/L,CK2000.00U/L,LDH9040U/L,Urea15.20mmol/L,SCr114.30μmol/L。急行抢救措施,终因呼吸心跳停止死亡。
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| 关 键 词： | 牛黄解毒片 不良反应 过敏性休克 死亡 |
Death from anaphylactic shock after taking Niuhuangjiedu tablets in a child |
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| Yang Yi,Sun Shubo,Lei Lili,Nie Lei.Death from anaphylactic shock after taking Niuhuangjiedu tablets in a child[J].Adverse Drug Reactions Journal,2010,12(2):147-147. |
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| Authors: | Yang Yi Sun Shubo Lei Lili Nie Lei |
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| Institution: | 1aDepartment of Pharmacy,1bPediatrics Department No.2,the First Affiliated Hospital of Jiamusi University,Jiamusi 154003,Heilongjiang Province,China) |
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| Abstract: | A boy aged one and a half years with constipation was given one tablet of Niuhuangjiedu by his parents themselves. One hour later,the child developed facial edema. Subsequently,he experienced convulsion,facial and peripheral cyanosis,respiratory and cardiac arrest,and he was then hospitalized. Physical examination showed a coma state,a sluggish light reflex,a respiratory rate of 60~80 breaths/min,and a blood pressure of 35/0 mm Hg. Laboratory tests revealed the following values：ALT 368.00 U/L,AST 2 000.00 U/L,CK 2 000.00 U/L,LDH 9 040 U/L,Urea 15.20 mmol/L,SCr 114.30 μmol/L. Resuscitations were given immediately and he died from respiratory and cardiac arrest. |
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| Keywords: | Niuhuangjiedu tablets adverse reactions anaphylactic shock death |
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