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| 环孢素血药浓度监测及其临床意义 | |
| 引用本文： | 邹晓华,俞聪聪,谷娜. 环孢素血药浓度监测及其临床意义[J]. 中国医院用药评价与分析, 2011, 0(7): 624-626 |
| 作者姓名： | 邹晓华 俞聪聪 谷娜 |
| 作者单位： | 解放军第117医院药剂科; |
| 摘 要： | 目的:监测肾移植患者环孢素(CsA)血药浓度,探讨其临床意义。方法:458例肾移植受者术后口服CsA达稳态时,用荧光偏振免疫分析法(FPIA)测定其全血CsA浓度。结果:随着移植肾存活时间的延长,CsA治疗浓度水平呈逐渐下降趋势。结论:每个患者的病情、用药情况都不尽相同。监测CsA血药浓度时必须结合患者的实际情况作具体分析,及时调整用药方案,确保正确地指导临床合理用药,提高治疗水平。 |
| 关 键 词： | 肾移植受者 环孢素 血药浓度 荧光偏振免疫分析法 |
Monitoring of Blood Concentration of Cyclosporine and Its Clinical Significance |
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| ZOU Xiao-hua,YU Cong-cong,GU Na. Monitoring of Blood Concentration of Cyclosporine and Its Clinical Significance[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2011, 0(7): 624-626 | |
| Authors: | ZOU Xiao-hua YU Cong-cong GU Na |
| Affiliation: | ZOU Xiao-hua,YU Cong-cong,GU Na(Dept.of Pharmacy,No.117 Hospital of PLA,Hangzhou 310013,China) |
| Abstract: | OBIECTIVE: To monitor blood concentration of cyclosporine(CsA) in renal transplantation recipients and discuss its clinical significance.METHODS: The whole blood concentration of CsA in 458 renal transplantation receivers who received oral CsA postoperatively was determined by Fluorescence Polarization Immunoassay(FPIA) when CsA concentration reached steady state.RESULTS: The blood concentration of CsA decreased as the increase of the survival time of the graft kidney.CONCLUSION: The state of illnes and med... |
| Keywords: | Renal transplantation recipient Cyclosporine(CsA) Blood concentration Fluorescence polarization immunoassay(FPIA) |
| 本文献已被 CNKI 维普 等数据库收录！ | |