多囊卵巢综合征中医证候及证候要素分布特点的文献研究

目的:通过现代文献研究,分析PCOS中医证候及证候要素的分布特点,为建立PCOS的辨证规范提供依据。方法:对2002—2013年的临床研究文献进行检索,分为调查研究和干预研究2类,建立数据库进行统计分析。结果:1)纳入181篇文献,其中调查研究48篇,干预研究133篇;2)调查类文献中,原始辨证结果 64种,涉及29种证候类型,出现频率在10%以上的依次为肾虚证、痰湿(浊)证、血瘀证、肝气郁结证和肾阳虚证;3)干预类研究文献中,原始辨证结果 50种,涉及22种证候类型,出现频率在10%以上的依次为肾虚证、痰湿(浊)证和血瘀证;4)2类文献中,病位类证候要素出现频率在5%以上的均为肾、肝、脾;病性类证候要素出现频率在5%以上的均有虚、痰湿(浊)、血瘀、气滞、阳虚,另外,调查类文献中还有阴虚,干预类文献中有火(热)。结论:临床中,对PCOS的辨证结论虽繁杂、各异,但涉及的证候要素相对集中;本研究所归纳、提炼之证候要素,可为制订该病的临床辨证规范提供依据。

Literature Research on TCM Syndrome and Syndrome Elements Distribution Pattern of Polycystic Ovary Syndrome

Objective： To summarize the distribution law of TCM syndromes and syndrome elements of PCOS and to provide evidence for accurate differentiation of PCOS by analyzing clinical literatures. Methods： We searched the clinical literatures on PCOS,built up a literature data-base by Excel software and ana1 yzed the data. Results： 1） Among the included 181 articles,there were 48 survey literatures and 133 intervention literatures. 2） Among the survey literatures,there were 64 kinds original diagnosis results,involving 29 kinds of syndromes. There were five kinds of syndromes whose frequency were more than 10%,namely kidney deficiency syndrome,phlegmdampness syndrome,blood stasis syndrome,stagnation of liver qi syndrome and deficiency of kidney yang syndrome. 3） Among intervention literatures,there were 50 kinds of original diagnosis results,involving 22 kinds of syndromes. There were three kinds of syndromes whose frequency were more than 10%,namely kidney deficiency syndrome,phlegm-dampness syndrome and blood stasis syndrome. 4）In two kinds of literature,the syndrome elements were relatively uniform. The syndrome elements of disease location whose frequency were more than 10% were kidney,liver and spleen. The syndrome elements of disease nature whose frequency were more than 10%mainly were deficiency,phlegm dampness（ turbidity）,blood stasis,qi stagnation,deficiency of Yang. In addition,there were Yin in survey literatures and fire（ heat） in intervention literatures. Conclusion： In clinical practice,the diagnosis results of PCOS are complicated and different,but the syndrome elements involved in the syndrome are relatively concentrated. In this study,the syndrome elements which are summarized and refined,can provide the basis for clinical syndrome specification.