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NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction
Authors:Yang Zhiqiong  Fuss Ivan J  Watanabe Tomohiro  Asano Naoki  Davey Michael P  Rosenbaum James T  Strober Warren  Kitani Atsushi
Affiliation:Mucosal Immunity Section, Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Abstract:
Keywords:APC, antigen-presenting cell   ELISA, enzyme-linked immunosorbent assay   EMSA, electrophoretic mobility shift assay   HVJ-E, Hemagglutinin Virus Japan-Envelope   IFN, interferon   IL, interleukin   LPS, lipopolysaccharide   MDP, muramyl dipeptide   MHC, major histocompatibility complex   NF-κB, nuclear factor κB   NOD2-Tg, NOD2 transgenic   PCR, polymerase chain reaction   PGN, peptidoglycan   TNBS, trinitrobenzene sulfonic acid   TNF, tumor necrosis factor   Wt, wild-type
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