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Relationship between the Mutation of IRS-1 Gene and β_3-adrenergic Receptor Gene
作者姓名:丁国宪  沈捷  陈家伟
作者单位:DING Guo xian,SHEN Jie,CHEN Jia weiDepartment of Endocrinology,the First Affiliated Hospital of Nanjing Medical University,Nanjing Jiangsu 210029,P.R. China
摘    要:Obesityisassociatedwithinsulinresis tance (IR) ,whichplaysacriticalroleinthedevelopmentoftype 2diabetesmellitus.ThemechanismofIRisrelatedtotheabnormalitiesofinsulinreceptor,pre receptor,post recep tor ,resultingindefectivemetabolicpathwayofglucose,lipidand pr…

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