Protective effects of royal jelly on testicular torsion induced ischaemia reperfusion injury in rats |
| |
| Authors: | Abolfazl Abbaszadeh Vahideh Assadollahi Masoud Alasvand Khatereh Anbari Negin Tavakoli Mohammadreza Gholami |
| |
| Affiliation: | 1. Department of Surgery, Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran;2. Cancer and Immunology Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran;3. Department of Social Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran;4. Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran;5. Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran |
| |
| Abstract: | ![]()
This study was performed to investigate the protective effects of royal jelly (RJ) on a testicular torsion-induced ischaemia/reperfusion (I/R) injury in adult rats. A total of 40 male Wistar rats were divided into four groups, including 10 rats in each group: Group 1 (sham), Group 2 (Control), group 3 (I/R rats treated with 100 mg/kg RJ for 50 days after torsion) and group 4( I/R rats treated with 20 mg/kg vitamin C for 50 days after torsion). Testicular torsion was created by rotating the right testes 720° a clockwise direction for 90 min. The levels of testosterone were measured by ELISA. Pathological evaluation, mean maturity and quality of the seminiferous tubules were used. Results showed that the testicular histopathology standards and testosterone levels changes were statistically significant in groups 3 and 4. The results obtained in this study may suggest that RJ like vitamin C had protective effects on a testicular ischaemia/reperfusion-induced injury in rats. |
| |
| Keywords: | ischaemia-reperfusion royal jelly testis torsion |
|
|
