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High-risk B-cell acute lymphoblastic leukaemia presenting with hypereosinophilia and acquiring a novel PAX5 fusion on relapse
Authors:Barbara J. McClure  Susan L. Heatley  Jacqueline Rehn  James Breen  Rosemary Sutton  Timothy P. Hughes  Ram Suppiah  Tamas Revesz  Michael Osborn  Daniel White  David T. Yeung  Deborah L. White
Affiliation:1. Cancer Program, Precision Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia;2. Cancer Program, Precision Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia

School of Medicine, University of Adelaide, Adelaide, SA, Australia

Australian and New Zealand Children's Oncology Group (ANZCHOG), Clayton, VIC, Australia;3. Cancer Program, Precision Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia

Faculty of Health and Medical Science, University of Adelaide, Adelaide, SA, Australia;4. Faculty of Health and Medical Science, University of Adelaide, Adelaide, SA, Australia

Computational and Systems Biology Program, SAHMRI, Adelaide, SA, Australia

Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia;5. Australian and New Zealand Children's Oncology Group (ANZCHOG), Clayton, VIC, Australia

Molecular Diagnostics, Children's Cancer Institute, Sydney, NSW, Australia

School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia

Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia;6. Women's and Children's Hospital, North Adelaide, SA, Australia;7. Australian and New Zealand Children's Oncology Group (ANZCHOG), Clayton, VIC, Australia

Women's and Children's Hospital, North Adelaide, SA, Australia

School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia;8. Australian and New Zealand Children's Oncology Group (ANZCHOG), Clayton, VIC, Australia

Australian Genomics Health Alliance (AGHA), Parkville, VIC, Australia

Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia

Women's and Children's Hospital, North Adelaide, SA, Australia;9. Faculty of Health and Medical Science, University of Adelaide, Adelaide, SA, Australia

Women's and Children's Hospital, North Adelaide, SA, Australia;10. Cancer Program, Precision Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, SA, Australia

School of Medicine, University of Adelaide, Adelaide, SA, Australia

Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia

Abstract:
Keywords:Leukaemia  B-ALL  hypereosinophilia  Ph-like  PAX5
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