| 葛根素与维生素C联用治疗糖尿病肾病的临床观察 |
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| 引用本文： | 张敏红,马爱民,洪云月,谢群莉,张文明.葛根素与维生素C联用治疗糖尿病肾病的临床观察[J].海峡药学,2007,19(1):58-60. |
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| 作者姓名： | 张敏红 马爱民 洪云月 谢群莉 张文明 |
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| 作者单位： | 1. 浙江省台州医院,台州,317000
2. 浙江省台州市中医院,台州,318000 |
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| 摘 要： | 目的探讨葛根素与维生素C联合应用对糖尿病肾病（DN）的影响及机制。方法将100例2型糖尿病患者随机分为葛极素加维生素C组和单纯葛根素组进行治疗观察，治疗前后检测尿蛋白排泄率（uAER）、血尿素IL（BUN）、血清肌酐（Scr）、空腹血糖、餐后2h血糖、糖化血红蛋白、平均动脉压。结果两组UAER均较治疗前有下降，以葛根素加维生素C组下降更为显著。结论葛根素联合维生素C对糖尿病肾病患者的治疗具有一定的临床意义。
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| 关 键 词： | 葛根素注射液 维生素C 糖尿病肾病 |
| 文章编号： | 1006-3765（2007）01-0058-03 |
Clinic effects of puerarin and vitamin C on diabetic nephropathy |
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| ZHANG Min-hong,MA Ai-min,HONG Yun-yue,XIE Qun-li,ZHANG Wen-ming.Clinic effects of puerarin and vitamin C on diabetic nephropathy[J].Strait Pharmaceutical Journal,2007,19(1):58-60. |
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| Authors: | ZHANG Min-hong MA Ai-min HONG Yun-yue XIE Qun-li ZHANG Wen-ming |
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| Institution: | 1. Taizhou Hospital of Zhejiang, Taizhou 317000, China ; 2. Taizhou Chinese traditional hospital of Zhejiang, Taizhou 318000, China |
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| Abstract: | OBJECTIVE To investigate the effects and mechanism of puerarin and vitamin C on diabetic nephropathy(DN).METHODS 100 patients with 2 type DN were divided into puerarin and vitamin C group and puerarin group.Before and after treatment,urinary albumin excretion rate (UAER),blood urea nitrogen(BUN),serum creatinine(Scr),free blood glucose(FBG),blood glucose after breakfast two hours,glycosylhemoglobin,and mean arterial pressure were messured.RESULTS After treatment, the levels of UAER were all decreased in two groups,but in puerarin and vitamin C group decreased more significant.CONCLUSION Puerarin with vitamin C had certain clinic effects in the treatment of diabetic nephropathy. |
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| Keywords: | Puerarin injection Vitamin C Diabetic nephropathy |
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