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免疫细胞化学在胸腹水细胞学诊断中的应用
引用本文:王雅如,朱云华,朱长乐,柳志向,包国祥,于振键.免疫细胞化学在胸腹水细胞学诊断中的应用[J].江苏大学学报(医学版),1999(4).
作者姓名:王雅如  朱云华  朱长乐  柳志向  包国祥  于振键
作者单位:江苏省中医院病理科!210029(王雅如,朱云华,朱长乐),江苏职工医科大学!210029(柳志向,包国祥),南京市第一卫生学校!210000(于振键)
摘    要:目的:探讨免疫细胞化学在细胞学诊断中的应用。方法:用常规技术和免疫细胞化学方法对70例胸腹水标本进行观察。结果:47例检出恶性和异型增生细胞,23例检测出良性和增生间皮细胞,CEA阳性率分别为55.3%,17.3%,差异显著。根据CEA、EMA、Keratin、Vimentin的表达有6例识别转移癌和增生间皮细胞。根据AFP、MG-7表达帮助确定6例肿瘤的原发灶。结论:免疫细胞化学能提高胸腹水细胞学诊断的准确性。

关 键 词:细胞学诊断  免疫细胞化学  胸水  腹水

Immunocytochemical Studies on Cytological Diagnosis of Ascites and Hydrothorax
Wang Yaru,Liu Zixiang,Zhu Yunhua et al.Immunocytochemical Studies on Cytological Diagnosis of Ascites and Hydrothorax[J].Journal of Jiangsu University Medicine Edition,1999(4).
Authors:Wang Yaru  Liu Zixiang  Zhu Yunhua
Abstract:objective: To explore the application of immnocytochemical methods in cytological diagnosis.Methods: Seventy cases of ascites and hydrothorax were investigated using routine techniques and immunocytochemical methods.Results: 47 cases were detected malignant and dysplasia cells.23 cases were detected benign and hyperplasia cells.The CEA positive rates were 55.3% and 17.3% respectively( P <0 05).According to the expressions of CEA,EMA,Keratin,Vimentin were diffrentiated between metastatic and hyperplasia mesothelial cells in 6 cases.According to the expressions of AFP,MG 7 were detected the locations of primary neoplasms in 6 cases.Conclusions: Immunocytochemistry may be increased the definete of cytological diagnosis.
Keywords:Cytological diagnosis  Ascites  Hydrothorax  Immunocytochemistry
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