A preliminary clinical study of bifidobacteria preparation on the treatment of diarrhea in severely burned patients.

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A preliminary clinical study of bifidobacteria preparation on the treatment of diarrhea in severely burned patients

Objective To investigate the role of bifidobacteria preparation in the prevention of diarrhea in severely burned patients.Methods Forty-three severely burned patients who were inflicted by diarrhea were included in this study. The changes of intestinal microflora were observed.Results The intestinal flora of all patients with diarrhea changed greatly before treatment. The proportions of bifidobacteria and bacteroid decreased significantly, whereas those of aerobe and Candida increased relatively. The ratio of anaerobe to aerobe decreased. As a result, the patients' intestinal flora were distorted. After six days treatment of bifidobacteria, diarrhea in most patients ceased and the intestinal microflora restored.Conclusion Bifidobacteria feeding plays an important role in restoring intestinal microflora and stopping diarrhea in severely burned patients.