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Structural particularities of parainfluenza type 1 (Sendai) virus progens obtained by cultivation in the presence of ceruloplasmin
Authors:E Tomas  S M Dumitrescu  A Popescu  N Cajal
Abstract:
Sendai virus multiplication in the presence of ceruloplasmin resulted in the appearance of qualitatively modified progens. There was an increase in the proportion of incomplete virus particles and a decrease in hemagglutinin and neuraminidase activities, in virus infectivity and antigenicity (with the exception of subviral fractions with predominant hemagglutinating activity). Virus progens obtained in the presence of ceruloplasmin had a higher sensitivity to detergent treatment; virus ghosts formed by re-aggregation of envelope fragments could be observed in the electron microscope.
Keywords:
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