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Tierexperimentelle untersuchungen zur karzinogeninduzierten tumorbildung an kolotomien in abhängigkeit von nahtmaterialien |
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| Authors: | T. Hupp H. Buhr S. Ivancovic N. Beck |
| Affiliation: | (1) Chirurgisches Zentrum der Universitat (Direktor: Prof. Dr. Ch. Herfarth), Kirschnerstraße 1, W-6900 Heidelberg, BRD;(2) Institut für Toxikologie und Chemotherapie am Deutschen Krebsforschungszentrum, Im Neuenheimer Feld 400, W-6900 Heidelberg, BRD;(3) Pathologisches Institut der Universitat (Direktor: Prof. Dr. H. F. Otto), Im Neuenheimer Feld 220, W-6900 Heidelberg, BRD |
| Abstract: | Summary To assess the possible risk of cancer in the operated colon after stapling compared with vicryl sutures, the influence of the nickel-containing staples was tested in caecum-resected and carcinogen-treated rats. The nickel-containing staples were seen as a cocarcinogen. The aim of the study was to determine whether a higher incidence of cancer occurs at the anastomotic suture line depending on stapler vs. vicryl sutures after subcutaneous application of carcinogens (dimethylhydrazine). The results show that there is no increased risk of cancer following mechanical stapling.Herrn Prof. Dr. Dr. h.c. mult. F. Linder zum 80. Geburtstag |
| Keywords: | Suture line carcinoma Colon cancer Stapler anastomoses Vicryl anastomoses Carcinogen treated rats |
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