口腔健康状况与冠心病关系的临床研究

目的探讨口腔健康状况与冠心病的相关关系；方法选取冠心病与非冠心病人各30例，方法：①比较两组间口腔健康状况的差异（包括牙周指数-PD、GI、PLI，牙周病牙数、缺牙数、龋病牙数）；②比较两组间龈下菌斑中血链球菌数和产黑色素茵群数的差异；③调查两组间与口腔健康和冠心病相关因素的差异（包括每天刷牙次数、口腔健康和冠心病关系知晓率、年龄、性别、文化程度、体重指数、吸烟、饮酒、嗜成食、规律运动习惯）。结果①单因素分析发现：两组在PD、PLI、牙周病牙数、缺牙数、龋病牙数、龈下菌斑中血链球菌可培养菌总数方面差异具有统计学意义（P〈0．05）；在每天刷牙次数、规律运动习惯及嗜成食方面差异也具有统计学意义（P〈0．05）；②Logistic多元逐步回归分析后，两组的龈下菌斑中血链球菌可培养菌总数和牙周袋探诊深度PD差异具有统计学意义（P〈0．05）。结论口腔健康状况尤其是牙周的健康状况与冠心病高度相关．应将牙周病的预防与控制提高到新的高度来认识，口腔科和心血管内外科医师都应将宣传、防治牙周病的知识作为自己应承担的责任与义务。

Relationship between oral health status and coronary heart disease

Objective To investigate the correlation of oral health status and coronary heart disease(CHD).Methods 30 patients with CHD and 30 people without CHD were compared with items such as oral health status(including periodontal index PD,GI and PLI),the number of tooth in peridontitis,the number of missing tooth and the number of caries),the amount of StreptococcusSanguis(S.s) and black-pigm ented bacterin(BPB) in subgingival plaque(SSp) and the related factors of CHD(including the frequency and method of teeth brushing,the knowing of the relationship between oral health status and CHD,age,gender,education,body mass index,smoking,drinking,salty food habit and regular exercise habit).Results Univariate analysis showed that there were statistic differences in PD,PLI,the number of tooth in peridontitis,the number of missing tooth,the number of caries and the amount of S.s in SSp,between two groups(P<0.05),and the two groups had statistic in the frequency of teeth brushing,regular exercise habit and salty food habit difference(P<0.05).The Logistic regression analysis showed that the amount of S.s in SSp and PD had statistic differences(P<0.05).Conclusion Oral health status especially the status of periodontal tissues had significant correlations with the incidence of CHD,so the important of prevention and control of peridontitis must be understood in a new view.Dentists and physicians should take the responsibility for spreading the knowledge of prevention and control of peridontitis.