Clinical assessment of oxygen delivery and consumption during hypotensive anaesthesia - A clinical application of The Deep Picture™

Usual evaluation of the relationship between oxygen delivery (DO₂) and oxygen uptake (VO₂) is based on the arterial oxygen tension (pO₂), oxygen saturation (sO₂), haemoglobin concentration (ctHb), the same indicators in mixed venous blood and cardiac output, sometimes supplemented by the expiratory carbon dioxide concentration. And, so far, the relationship among DO₂, VO₂ and the new parameters for an evaluation of oxygen status (oxygen extraction tension: p_K, concentration of extractable oxygen: c_x, oxygen compensation factor: Q_x) (1) has not been discussed enough.
Therefore, this study was designed to evaluate whether the new parameters give the clinically significant information to analyse the relationship between DO₂ and VO₂ during the acute haemodynamic change with intentionally induced hypotension in anaesthetized adult patients.