自拟平喘汤应用于小儿支气管哮喘对患儿肺功能保护及免疫功能恢复的影响

目的：分析自拟平喘汤应用于小儿支气管哮喘对患儿肺功能保护及免疫功能恢复的影响。方法：选择2014年7月~2016年6月在我院接受治疗的小儿支气管哮喘患儿80例为本次研究对象，所有患儿随机分为观察组40例、对照组40例。对照组患儿给予西医常规治疗，观察组患者在此基础上给予自拟平喘汤治疗。观察两组患儿治疗后的总体疗效和治疗前后临床症状积分、肺功能指标、免疫功能指标、T淋巴细胞的变化。结果：观察组患儿的总体疗效（95.00%）高于对照组患儿（75.00%），差异有统计学意义（P＜0.05）；治疗后，两组患儿临床症状积分均有所下降，观察组（1.96±0.84）分低于对照组（3.57±1.23）分，差异具有统计学意义（P＜0.05）；两组患儿的FEV1、PEF、FEV1/FVC水平均有所上升，观察组［（2.20±0.35）L、（4.35±0.67）L/S、（79.50±6.83）%］高于对照组［（1.89±0.43）L、（3.84±0.56）L/S、（68.08±8.57）%］，差异具有统计学意义（P＜0.05）；两组患儿的CD4+、CD4+/CD8+评分有所下降，观察组［（41.79±3.82）%、1.32±0.36］低于对照组［（45.11±5.67）%、1.61±0.45］，差异有统计学意义（P＜0.05）；两组患儿的CD8+水平有所上升，观察组［（33.92±7.77）%］高于对照组［（29.87±5.54）%］，差异有统计学意义（P＜0.05）；两组患儿的CD69+CD3+T、CD69+CD4+T平均有下降，观察组［（6.88±0.90）%、（3.81±0.64）%］低于对照组［（9.07±0.86）%、（5.37±0.58）%］，差异有统计学意义（P＜0.05）。结论：自拟平喘汤对小儿支气管哮喘具有确切的疗效，能够有效减轻患儿的临床症状，保护患儿的肺功能，调节细胞免疫功能，具有较好的推广应用价值。

Effect of self-made pingchuan Tang on childhood lung function protection and immune function recovery in children with bronchial asthma

Objective:To analyze the effect of self-made Pingchuan Tang on pediatric bronchial asthma in children with pulmonary function protection and immune function recovery.Methods: 80 children with bronchial asthma in our hospital from July 2014 to June 2016 were selected.They were randomly divided into observation group (n=40) and control group (n=40).The patients in the control group were given routine treatment of western medicine.On the basis of this,the patients in the observation group were treated with Pingchuan Tang.The overall curative effect,the clinical symptom score,pulmonary function index,immune function index,T lymphocyte changes after treatment were observed.Results: The overall curative effect (95.00%) in the observation group was higher than that in the control group (75.00%),the difference was statistically significant (P<0.05).After treatment,the clinical symptom scores of the two groups decreased,the observation group (1.96±0.84) was lower than the control group (3.57±1.23),the difference was statistically significant(P<0.05).After treatment,FEV1,PEF,FEV1/FVC levels were increased in both groups,the observation group ［（2.20±0.35）L,（4.35±0.67）L/s,（79.50±6.83）%］ were significantly higher than those in the control group［（1.89±0.43）L,（3.84±0.56）L/s,(68.08±8.57)%］,the difference was statistically significant (P<0.05).After treatment,the CD4+，CD4+/CD8+ scores of the two groups decreased,the observation group［(41.29±3.82）%,1.32±0.36］ was lower than that in the control group ［(45.11±5.67）%,1.61±0.45］,the difference was statistically significant (P<0.05).After treatment,the two groups of children with CD8+ levels had increased,the observation group ［(33.92±7.77)%］ was higher than that in the control group ［(29.87±5.54)%］,the difference was statistically significant (P<0.05).After treatment,the two groups of children with CD69+CD3+T，CD69+CD4+T levels were decreased,the observation group ［(6.88±0.90)%,(3.81±0.64)%］ was lower than the control group ［(9.07±0.86)%,（5.37±0.58）%］,the difference was statistically significant (P<0.05).Conclusion: Self-made Pingchuan Tang has definite effect on pediatric bronchial asthma,which can effectively alleviate the clinical symptoms of patients,protect the lung function of children,regulate cell immune function,and have good application value.