| 放射性球囊治疗冠状动脉再狭窄时导管内核素对正常血管的剂量分布计算 |
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| 引用本文： | 徐志勇,张良安,戴光复,苑淑渝,王丹,范亚光.放射性球囊治疗冠状动脉再狭窄时导管内核素对正常血管的剂量分布计算[J].中国辐射卫生,2002,11(4):198-199,201. |
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| 作者姓名： | 徐志勇 张良安 戴光复 苑淑渝 王丹 范亚光 |
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| 作者单位： | 中国医学科学院放射医学研究所,天津,300192 |
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| 基金项目： | 国家自然科学基金资助项目 (30 70 2 33) |
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| 摘 要： | 目的：计算放射性球囊治疗冠状动脉再狭窄时导管内核素对正常血管的剂量分布。方法：用Loevinger公式计算球囊、导管周围组织的剂量分布。结果：导管周围组织与球囊周围组织的剂量之比在整个经向距离范围内接近于1／10。正常治疗时，导管周围血液受到的平均剂量达到5．36Gy，血管壁受到的平均剂量达到1．62Gy。结论：用放射性球囊治疗冠状动脉再狭窄时，正常血管短期和长期辐射效应应该被考虑。
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| 关 键 词： | 冠状动脉再狭窄 血管 剂量分布 放射性球囊 剂量点核函数 蒙特卡罗方法 血管成形术 近距离放射治疗 |
| 文章编号： | 1004-714X(2002)04-0198-02 |
Dosimetry of Dose Distribution in Normal Vessels Brought by Radioactive Solution in the Catheter for Intracoronary Restenoisis In-tra- balloon Brachytherapy |
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| XU Zhi-yong,ZHANG Liang-an,DAI Guang-fu,et al..Dosimetry of Dose Distribution in Normal Vessels Brought by Radioactive Solution in the Catheter for Intracoronary Restenoisis In-tra- balloon Brachytherapy[J].Chinese Journal of Radiological Health,2002,11(4):198-199,201. |
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| Authors: | XU Zhi-yong ZHANG Liang-an DAI Guang-fu |
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| Institution: | XU Zhi-yong,ZHANG Liang-an,DAI Guang-fu,et al.Institute of Radiation Medicine,Chinese Academy of Medical Sciences and Beijing Union Medicine College,Tianjin 300192,China. |
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| Abstract: | Objective To estimate dose distribution in normal vessels delivered by radioactive solution in the catheter for intracoronary intra-balloon brachytherapy.Methods The dose distribution of normal tissue around balloon and catheter were estimated by the dose kernel function of Loevinger.Results The ratio of tissue around catheter to balloon was about 1/10.The average dose of blood around catheter and around vascular wall is 5.36 Gy,1.62 Gy respectively.Conclusion The long-term and short-term effects would be considered when restenosis of intracoronary is treated with the method of radioactive balloon. |
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| Keywords: | Radioactive Balloon Restenosis Dose Kernel Function Monete Carlo Method |
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