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维思通与舒必利治疗精神分裂症阴性症状的对照研究
引用本文:唐本玲,高俊,何先富. 维思通与舒必利治疗精神分裂症阴性症状的对照研究[J]. 四川医学, 2008, 29(2): 178-179
作者姓名:唐本玲  高俊  何先富
作者单位:江油市精神病医院,四川,江油,621700
摘    要:
目的 探讨维思通治疗精神分裂症阴性症状的疗效及不良反应.方法 采用随机对照研究方法,用维思通和舒必利分别治疗以阴性症状为主的精神分裂症.疗程12周,以简明精神病评定量表(BPRS)、阴性症状评定量表(SANS)评定疗效,以治疗中需处理的不良反应症状量表(TESS)评定药物不良反应.结果 两药对精神分裂症阴性症状疗效近似,维思通对意志缺乏、兴趣缺乏及社交缺乏改善明显,不良反应少且轻微.结论 维思通对精神分裂症阴性症状有一定疗效.

关 键 词:维思通  舒必利  精神分裂症  阴性症状
文章编号:1004-0501(2008)02-0178-02
收稿时间:2007-09-28
修稿时间:2007-09-28

A comparative study on Risperidone and sulpiride in treating schizophrenia whose prdominant clinical features were negative symptoms
TANG Ben-ling,GAO Jun,HE Xian-fu. A comparative study on Risperidone and sulpiride in treating schizophrenia whose prdominant clinical features were negative symptoms[J]. Sichuan Medical Journal, 2008, 29(2): 178-179
Authors:TANG Ben-ling  GAO Jun  HE Xian-fu
Abstract:
Objective To compare the clinical efficacy and side effects of risperidone and sulpiride in the treatment of schizophrenia with predominantly negative symptoms. Methods two hundred schizophrenic inpatients with predorminantly negative symptoms were randomly assigned to fispefidone group or sulpifide group for 12 weeks. The clinical efficacy and side effects were evaluated with BPRS,SANS,and TESS respectively.Results the clinical efficacy of fispefidone and sulpifide are similar,but fispefidone was more efficacy for treatment of abulia, interest deficiency and social withdrawal. The side effects of fispefidone are few. Conclusion fisperidone is highly effective to treat engative symptoms of sehizophrenia.
Keywords:risperidone   sulpifide   schizophrenia   negative   symptoms
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