Preparation of Carbamoyl Derivatives of Indole and of Derivatives of 1,2,4-Triazol-3-one from Semicarbazides |
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Authors: | Karol Butkiewicz Jan Wojciechowski Ryszard Pakula |
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Abstract: | ![]() A simple and one-step method for the preparation of the title compounds is described. Semicarbazides 2 react easily with levulinic acid in the presence of HCl to give 4 , whereas in a alkaline medium they cyclize to form the triazole derivatives 3 . |
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