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H-Y antigen generating and receptor systems in abnormal sexual development |
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| Authors: | C. A. Moreira-Filho O. Frota-Pessoa Angela M. Vianna-Morgante T. H. Chu H. Bisi T. R. Gollop John M. Opitz |
| Abstract: | This paper reports data from one case of XY gonadal dysgenesis and one case of XY mixed gonadal dysgenesis. Their H-Y antigen expression was determined on peripheral blood leukocytes and on gonad-derived fibroblasts. The former case was found to be H-Y negative while the latter was H-Y positive. The origin of these disorders is discussed in terms of mutations affecting the H-Y antigen generating and receptor systems. |
| Keywords: | H-Y antigen XY gonadal dysgenesis mixed gonadal dysgenesis |