308例脑动脉狭窄分布及相关危险因素分析

目的研究不同年龄段脑动脉狭窄(闭塞)的血管分布及其与相关危险因素的相关性。方法将308例经DSA和/或CTA诊断为脑动脉狭窄/或闭塞的缺血性脑卒中患者依据年龄分为青年组、中年组和老年组,对其颅内外动脉的狭窄程度、分布特征及特点等进行比较,同时测血压、血糖(GLU)、甘油三酯(TC)、总胆固醇(TG)及同型半胱氨酸,与无脑动脉狭窄组比较以上相关因素的差异。结果颅内动脉狭窄率(54.6%)明显高于颅外动脉(35.12%),比较脑动脉存在狭窄与无狭窄的两组缺血性脑卒中患者,血压、GLU、TG、TC、同型半胱氨酸、年龄因素差异有统计学意义(P<0.05或P<0.01),Logistic回归发现高血压、糖尿病,血脂异常、高同型半胱氨酸、吸烟、酗酒与缺血性脑卒中脑动脉狭窄呈明显相关性(P<0.05)。结论缺血性脑卒中患者颅内动脉狭窄发生率高于颅外动脉,高血压、糖尿病、血脂异常、高同型半胱氨酸、吸烟、酗酒与脑动脉狭窄均相关,是脑动脉狭窄的危险因素。

Distribution and analysis of related risky factor of intra and extra cranical arterial stricture in 308 patients with ischemic cerebrovascular disease

Objective To research different age paragraph brain artery stenosis(block) vessels distribution and associated risk factors of relevancy.Methods 308 cases with DSA and/or CTA diagnosed with cerebral artery stenosis/or occlusion ischaemic stroke patients according to age into youth,middleaged group and the elderly group,the outside the narrow intracranial arteries degree,distribution and characteristics are compared.Meanwhile measure blood pressure,blood sugar(GLU),triglycerides(TC),total cholesterol(TG) and homocysteine,and no brain artery stricture above group compared the factors relating to the differences.Results Intracranial artery stenosis rate(54.6%) was significantly higher than extracranial artery(35.12%),compared with the existing brain artery stenosis without narrow two groups of ischemic stroke patients,blood pressure,GLU and TG,TC,homocysteine,age factor differences have statistically significant(P<0.05 or P<0.01).Logistic regression found high blood pressure,diabetes,dyslipidemia,high homocysteine,smoking,excessive drinking and ischaemic stroke cerebral artery stenosis was significantly associated(P<0.05).Conclusion The incidence of stenosis of intracranial artery is higher than that of extracranial artery with cerebral artery stenosis of ischemic cerebrovascular disease,especially in young aged.High blood pressure,diabetes,dyslipidemia,high homocysteine,smoking,excessive drinking and cerebral artery stenosis were related,is the brain artery stenosis risk factors.