| 钛对体外培养的大鼠及人肝,肾细胞的毒性初探 |
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| 引用本文： | 潘美萍,董胜璋.钛对体外培养的大鼠及人肝,肾细胞的毒性初探[J].环境与健康杂志,1992,9(2):78-79. |
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| 作者姓名： | 潘美萍 董胜璋 |
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| 作者单位： | 广州中山医科大学卫生学院 510089
(潘姜萍，董胜璋)，广州中山医科大学卫生学院 510089(陈成章) |
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| 摘 要： | 用体外培养的大鼠肝细胞,人胎肝、肾细胞检测钛的毒性,测定其毒性终点和中毒后肝、肾细胞的形态改变。结果:高稀释度的钛对肝肾培养细胞均有毒性作用。中毒后的细胞出现水肿、边界模糊和消失;细胞核水肿、不规则,胞浆颗粒增多呈衰老现象,提示钛进入人体引起的肝肾慢性蓄积毒作用不容忽视。
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| 关 键 词： | 钛 细胞毒性 环境毒理学 |
Primary Research on Cellular Toxicity of Hepatocytes and Renal Cells of Rat and Human Embryo by Titanium in Vitro |
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| Pan Jiangping et al.Primary Research on Cellular Toxicity of Hepatocytes and Renal Cells of Rat and Human Embryo by Titanium in Vitro[J].Journal of Environment and Health,1992,9(2):78-79. |
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| Authors: | Pan Jiangping |
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| Institution: | Pan Jiangping et al |
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| Abstract: | In this paper, we have observed the toxic effect to hePatocytes and renal cells of rat and human embryo by titanium in vitro.The results have showed that the toxic effect was Present by titanium in lower concentration. The morphalogical changs were observed in cells exposed to titanium, such as cytoplasm edema, disappear Cell border, nuclear edema, the granules increased in cytoplasm and cell senescence. This experiment indicated that the chronic cumulation of titanium to liver and kidney do not neglected. |
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| Keywords: | Titanium Cellular toxicity |
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