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紫外可见分光光度法测定阿托伐他汀钙片含量
引用本文:蒲强红,姜成,吕秋菊.紫外可见分光光度法测定阿托伐他汀钙片含量[J].安徽医药,2009,13(3):273-274.
作者姓名:蒲强红  姜成  吕秋菊
作者单位:乐山职业技术学院护理系,四川乐山,614000;浙江金立源药业有限公司,浙江上虞
摘    要:目的建立紫外可见分光光度法测定阿托伐他汀钙片含量。方法采用246nm波长、乙醇为空白对照。结果阿托伐他汀钙片的线性范围为3.13~20.90mg·L。(r=0.9999),平均回收率为98.7%、RSD为0.9%(n=9)。结论该方法简便、快速、准确,可用于阿托伐他汀钙片的含量测定。

关 键 词:阿托伐他汀钙  紫外可见分光光度法

Determination of atorvastatin calcium tablet by ultraviolet and visible spectrophotometry
PU Qiang-hong,JIANG Cheng,LV Qiu-ju.Determination of atorvastatin calcium tablet by ultraviolet and visible spectrophotometry[J].Anhui Medical and Pharmaceutical Journal,2009,13(3):273-274.
Authors:PU Qiang-hong  JIANG Cheng  LV Qiu-ju
Institution:PU Qiang-hong1,JIANG Cheng2,LV Qiu-ju1 (1.Nursing Department,Leshan Vocational & Technical College,Leshan,Sichuan Province 6140002.Zhejiang kinglyuan Pharmaceutical Co Ltd,Shangyu,Zhejiang Province 312369)
Abstract:Aim To establish a for determination of atorvastatin calcium tablet by ultraviolet and visible spectrophotometry. Methods Atorvastatin calcium was detected at 246 nm by UV-Vis. Results The good linearity was obtained for atorvastatin calcium over the range of 3.13 - 20.90 mg · L^- 1 ( r = 0. 999 9 ). The average recovery was 98.7% lvith an RSD of 0.9%. Conclusion This method is simple, rapid and accurate for the determination of atorvastatin calcium tablet.
Keywords:atorvastatin calcium  ultraviolet and visible spectrophotometry  
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