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多发性硬化的治疗进展
引用本文:张留福,黄琼,楚兰.多发性硬化的治疗进展[J].中国临床药理学与治疗学,2007,12(5):499-503.
作者姓名:张留福  黄琼  楚兰
作者单位:1. 贵阳医学院附属医院神经内科,贵阳,550004,贵州
2. 中南大学临床药理研究所,长沙,410078,湖南
摘    要:多发性硬化是发生于中枢神经系统的由免疫介导的慢性自身免疫性脱髓鞘疾病。本病病因不明,可能与病毒感染和自身免疫功能紊乱等有关。其治疗方案仍不十分成熟,本文将主要从免疫干预治疗、基因治疗、干细胞移植治疗和其他治疗等四个方面对该病的治疗进展作一综述。

关 键 词:多发性硬化  免疫干预治疗  基因治疗  干细胞移植治疗
文章编号:1009-2501(2007)05-0499-05
修稿时间:2007-04-022007-05-01

Progress in treatment of multiple sclerosis
ZHANG Liu-fu,HUANG Qiong,CHU Lan.Progress in treatment of multiple sclerosis[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2007,12(5):499-503.
Authors:ZHANG Liu-fu  HUANG Qiong  CHU Lan
Institution:1Neurology Department of Affiliated Hospital, Guiyang Medical College, Guiyang 550004, Guizhou, China ; 2Clinical Pharmacological Institute of Central South University, Changsha 410078, Hunan, China
Abstract:Multiple sclerosis is a demyelinating disease affecting central nervous system induced by a chronic autoimmune disorder. Its exactly etiological mechanism remains unknown. Viral infection and autoimmunity functional disorder may be one of the reasons. In this article, we mainly reviewed the progress in the treatment of the disease including immune depressant, gene therapy, transplant therapy of stem cells and other therapies.
Keywords:multiple sclerosis  immunologic intervention therapy  gene therapy  stem cellular transplant therapy
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